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Page 1
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Among authors: poganik jr. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
Biological age is increased by stress and restored upon recovery.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Poganik JR, et al. Cell Metab. 2023 May 2;35(5):807-820.e5. doi: 10.1016/j.cmet.2023.03.015. Epub 2023 Apr 21. Cell Metab. 2023. PMID: 37086720 Free PMC article.
Validation of biomarkers of aging.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. Moqri M, et al. Among authors: poganik jr. Nat Med. 2024 Feb;30(2):360-372. doi: 10.1038/s41591-023-02784-9. Epub 2024 Feb 14. Nat Med. 2024. PMID: 38355974 Free PMC article. Review.
DNA methylation networks underlying mammalian traits.
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter G, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chavez AS, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke S, Cook JA, Cooper LN, Cossette ML, Day J, DeYoung J, Dirocco S, Dold C, Dunnum JL, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Fei Z, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Goya RG, Grant MJ, Green CB, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaître JF, Levine AJ, Li X, Li C, Lim AR, Lin DTS, Lindemann DM, Liphardt SW, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Murphy WJ, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Nie… See abstract for full author list ➔ Haghani A, et al. Among authors: poganik jr. Science. 2023 Aug 11;381(6658):eabq5693. doi: 10.1126/science.abq5693. Epub 2023 Aug 11. Science. 2023. PMID: 37561875
Redox Signaling by Reactive Electrophiles and Oxidants.
Parvez S, Long MJC, Poganik JR, Aye Y. Parvez S, et al. Among authors: poganik jr. Chem Rev. 2018 Sep 26;118(18):8798-8888. doi: 10.1021/acs.chemrev.7b00698. Epub 2018 Aug 27. Chem Rev. 2018. PMID: 30148624 Free PMC article. Review.
Interrogating Precision Electrophile Signaling.
Poganik JR, Long MJC, Aye Y. Poganik JR, et al. Trends Biochem Sci. 2019 Apr;44(4):380-381. doi: 10.1016/j.tibs.2019.01.006. Epub 2019 Feb 11. Trends Biochem Sci. 2019. PMID: 30765181 Free PMC article.
We need to shift the focus of aging research to aging itself.
Poganik JR, Gladyshev VN. Poganik JR, et al. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2307449120. doi: 10.1073/pnas.2307449120. Epub 2023 Sep 8. Proc Natl Acad Sci U S A. 2023. PMID: 37682890 Free PMC article. No abstract available.
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA. Griffin PT, et al. Among authors: poganik jr. Nat Aging. 2024 Feb;4(2):261-274. doi: 10.1038/s43587-023-00555-2. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200273
23 results